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Literature summary for 2.7.8.43 extracted from

  • Liu, L.; Li, Y.; Wang, X.; Guo, W.
    A phosphoethanolamine transferase specific for the 4-phosphate residue of Cronobacter sakazakii lipid A (2016), J. Appl. Microbiol., 121, 1444-1456 .
    View publication on PubMed
Search for more literature for 2.7.8.43

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Cronobacter sakazakii

Organism

Organism UniProt Comment Textmining
Cronobacter sakazakii
-
-
-
Cronobacter sakazakii BAA894
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diacylphosphatidylethanolamine + alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
-
 Cronobacter sakazakii diacylglycerol + 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
-
 ?
diacylphosphatidylethanolamine + alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
-
 Cronobacter sakazakii BAA894 diacylglycerol + 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A
-
 ?

Synonyms

Synonyms Comment Organism
EptA
-
 Cronobacter sakazakii
ESA_RS09200
-
 Cronobacter sakazakii

General Information

General Information Comment Organism
physiological function gene product of ESA_RS09200 in Cronobacter sakazakii encodes a phosphoethanolamine transferase that specifically adds a phosphoethanolamine to the 4'-phosphate residue of lipid A, but is not regulated by the PmrA-PmrB system. phosphoethanolamine modification of lipid A reduces recognition and killing by the host innate immune system Cronobacter sakazakii